Bill Keene has for many years lectured in architecture and urban studies specializing in the history of architecture in the United States with a special interest in the work of Frank Lloyd Wright. Bill for several years taught in an urban studies program at the University of Southern California, and he also taught urban history at Pepperdine University. Beginning a decade ago, Bill began developing and presenting tours and lectures dealing with architecture, infrastructure, sustainability, and design for the Smithsonian Associates. He has also presented lectures, seminars and tours at the National Building Museum, the Oasis Institute, the North American Festival of Wales and other groups and institutions.

His efforts have examined the life and work of Philip Johnson, the importance and evolution of the L'Enfant plan for Washington DC, the life and work of Montgomery Meigs (including a lecture filmed by C-SPAN). Bill has a special interest in and developed several lectures and tours on Frank Lloyd Wright including two day-long seminars on Wright at the Smithsonian and three Wright seminars at North American Festival of Wales. Other tours have dealt with a wide range of topics including: several multi-day tours of Frank Lloyd Write buildings in Chicago, Madison, Buffalo, and Pennsylvania; the history of the National Mall; infrastructure; country houses in England and the United States; modern architecture at Yale, the High Line, the Cooper Hewitt; midcentury modern architecture; urban farming and sustainability; and the history of architecture in America. Bill has a keen interest in all eras and phases of architecture from ancient times to cutting edge contemporary projects, from vernacular architecture to green buildings and the built environment in general.